Recent Articles
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When the Most Common Liver Disease Became Treatable
MASLD can no longer be treated as a low-priority diagnosis of exclusion. It is a screenable, stratifiable, and increasingly treatable disease.
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Why Exercise Cannot Outrun an Ultra-Processed Plate
Diet quality and physical activity are parallel, non-interchangeable pillars of long-term health, and no amount of exercise reliably outruns an ultra-processed plate.
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The Monthly Rhythm Hiding in Every Glucose Curve
Estradiol generally enhances insulin action, whereas progesterone opposes it, producing a modest luteal-phase rise in glucose and fall in insulin sensitivity.
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The Quiet Toll Visceral Fat Takes on the Brain
Sustained visceral fat loss, independent of total weight change, is associated with attenuated brain atrophy and preserved cognitive performance years later.
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The Risk a Zero Calcium Score Cannot See
Lp(a) and CAC provide independent, additive prognostic information, and a favorable calcium score should refine, not override, the intensity of management.
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The PCSK9 Inhibitor That Finally Fits in a Pill Bottle
Its significance lies less in a new mechanism than in a new delivery paradigm that could meaningfully expand access to potent LDL-C lowering.
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The Peptide That Follows Inflammation Into the Gut
A druggable, inflammation-seeking transporter system operating at the gut barrier is worth continued attention regardless of what happens to KPV specifically.
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The Immune Signals That Shape Mood and Memory
The immune-brain interface represents a critical regulatory nexus at the intersection of physical and mental health.
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When a Safe Supplement Stops Being Safe for the Longevity Patient
Modifiable metabolic factors, including over-the-counter supplements long considered safe, may carry unrecognized neurological risk.