Tag: Oxidative Stress
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Intermittent Fasting and Hair Loss: Molecular Mechanisms and Protective Countermeasures to Preserve Hair Follicle Regeneration
Intermittent fasting suppresses hair follicle stem cell regeneration through adipocyte lipolysis and oxidative stress, yet emerging interventions including antioxidant supplementation, hormonal pathway modulation, and refined fasting protocols offer viable strategies to mitigate hair loss while preserving metabolic benefits.
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From Conception to Prevention: How Metabolic Mastery Before Pregnancy Could Revolutionize Cerebral Palsy Prevention
Groundbreaking research reveals that optimizing parental metabolic health—controlling diabetes, obesity, and inflammation—before conception could prevent thousands of cerebral palsy cases globally.
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Oxidized Linoleic Acid: The Hidden Driver of Modern Metabolic Crisis
Modern Western diets contain 20-30 times more linoleic acid than a century ago, primarily from processed seed oils. This dramatic shift has generated oxidized linoleic acid metabolites (OXLAMs) that trigger mitochondrial dysfunction, inflammatory cascades, and insulin resistance through distinct biochemical pathways. Unlike saturated fats that primarily activate ceramide-PKC pathways, linoleic acid promotes oxidative stress-induced metabolic…